The International Society of Hypertension (ISH) has published its 2026 Global Hypertension Practice Guidelines in the Journal of Hypertension, introducing important updates six years after the previous edition. Eight key takeaways: 1 Elevated BP is now explicitly recognized. Office BP of 130–139/80–89 mmHg requires…
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La International Society of Hypertension (ISH) publicó sus nuevas Global Hypertension Practice Guidelines 2026 en el Journal of Hypertension. Seis años después de la versión de 2020, actualiza el diagnóstico, las metas…
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The American College of Cardiology has released its 2026 Expert Consensus Decision Pathway on Resistant Hypertension, published in JACC. This document provides a practical framework to translate evidence into clinical…
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A new network meta-analysis published in JACC: Advances provides important evidence — and a reminder to interpret comparative effectiveness carefully. Laino and colleagues evaluated 35 randomized trials involving 8,648…
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A timely State-of-the-Art Review by Khan and colleagues in CJASN provides a comprehensive look at how the management of resistant hypertension is evolving. The first step remains fundamental: Is this truly resistant…
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A timely Review in Nature Reviews Nephrology places the aldosterone–mineralocorticoid receptor (MR) axis at the center of the cardiovascular–kidney–metabolic (CKM) continuum. The concept is compelling: inappropriate MR…
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A new drug-level network meta-analysis including 10 RCTs and 2,865 patients provides an interesting perspective on therapies targeting the aldosterone-related sodium-retention pathway. Compared with placebo, office…
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For years, pharmacologic targeting of aldosterone has largely meant blocking its action at the mineralocorticoid receptor. Now, aldosterone synthesis itself has become a therapeutic target. In a timely article published…
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In obstructive sleep apnoea, that question may be more important than we think. A timely review by Gruber et al. in the European Respiratory Review highlights a frequently overlooked phenotype: nocturnal hypertension…
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